How Does HGH Work?

Now that you’re familiar with the history of medical use of HGH, we’ll take a look at how HGH works to achieve certain objectives. The effects of Human Growth Hormone on the impacted tissues of the human body can generally be described as anabolic.  Anabolic refers to a synthetic phase of metabolism known for building up tissues and organs. Human Growth Hormone is a protein hormone.  As such, it acts by working together with a specific receptor on the surface of cells.  These anabolic interactions of HGH with the cells’ receptors work in similar ways to solve very different problems.  Below are descriptions of how Human Growth Hormone works to alleviate specific symptoms, followed by case studies of real patients who have experienced results.  

Pediatric Human Growth Hormone Deficiency (PHGHD)

Pediatric Human Growth Hormone Deficiency occurs in an estimated 10,000 to 15,000 children in the United States alone.  Though most short children do not necessarily have a growth problem, a child growing at a much slower than normal rate can signify PHGHD.  This condition exists when pituitary growth hormone production is absent, has slowed or stopped completely.  

Adult Human Growth Hormone Deficiency (AHGHD)

Though adults don’t rely on natural Growth Hormone production for growth as children do, their bodies do depend on it for other purposes.  In adults, it is necessary to sustain healthy body composition and metabolism.  When an adult’s pituitary gland does not secrete enough of this important hormone, the body can have trouble maintaining a normal fat to muscle ratio, bad to good cholesterol levels, and appropriate bone mineral density.  

Treatment with Human Growth Hormone

Increased height during childhood is the most commonly recognized effect of Human Growth Hormone. Height in growing children appears to be stimulated by at least two mechanisms:

• Polypeptide, (a peptide containing anywhere from ten to more than one hundred amino acids) hormones are not fat-soluble.  Hence, they cannot penetrate the cell membrane of the muscle cell. Thus, HGH applies some of its effects by binding to receptors on target cells, where it activates a second messenger.  Through this mechanism GH directly stimulates division and multiplication of cells and tissues.

• Growth Hormone also stimulates production of Insulin-Like Growth Factor 1(IGF-1, a hormone homologous to proinsulin. The liver is a chief target organ of GH for this process and is the principal site of IGF-1 production. IGF-1 has growth-stimulating effects on a wide variety of tissues. Additional IGF-1 is generated within target tissues. IGF-1 also has stimulatory effects on osteoblast and chondrocyte activity to promote bone growth.

Children diagnosed with Pediatric Human Growth Hormone Deficiency are treated with HGH injections until accelerated growth brings the patient to normal size levels.

Likewise, adults with Adult Human Growth Hormone Deficiency are treated with HGH injections until body mass and cholesterol level ratios reach normal levels and proper bone density is achieved.  

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PHGHD Case Study – “Anna”

Anna’s mother knew something was definitely wrong.  Anna had always been on the small side, but at age 10, she seemed to stop growing altogether.  Her sister, who was two years younger, was suddenly taller than her.  Kids in her class were calling her names like “shorty” and “midget.”  At this point, Anna’s parents and pediatrician decided to work with a pediatric endocrinologist and start testing for various conditions.  They started by reviewing her growth chart and examining the family’s medical history.  Next, they had blood work done in order to examine various hormone levels.  A bone-age (x-ray of the hand) was taken in order to evaluate the size of bone openings in children that close up with growth.  This x-ray told the pediatric endocrinologist that Anna’s “bone age” was 7.  At this point, an MRI of Anna’s head was taken in order to rule out any brain tumors.  During the entire process, Anna and her parents were reassured by the medical staff that all phases of the testing were very routine. 

When Anna was diagnosed with Pediatric Human Growth Hormone Deficiency, her parents were crushed.  The thought of regular injections for their daughter conflicted Anna’s parents greatly.  They wondered if it would be okay for their daughter to just be a shorter person.  The pediatric endocrinologist explained the repercussions of letting PHGHD go untreated, including morbidity and death.  Shortly thereafter, Anna began HGH injection therapy.

Anna needed daily injections, so after a few weeks of being on the treatment, the doctor trained her mother to administer the HGH injections.  After three months, the endocrinologist saw that progress was being made and he adjusted the dose.   At the end of the second three-month period, Anna had grown a total of 5.4 inches!  She was almost at a normal height level for children her age, and she was very well adjusted to taking the daily injections. 

Today, Anna looks no different than her classmates.  She still has to take daily injections, as most children continue to take them through their teenage years until growth is expected to stop.  

AHGHD Case Study – “Gene”

Gene suffered from Growth Hormone Deficiency as a child and was treated with HGH injections.  After completing therapy (and growth), he spent almost ten years with Human Growth Hormone.  Toward the second half of the near-decade, Gene started to notice that he lacked energy.  He began to feel physically drained and lethargic.  He also noticed that his “tiredness” was leading to an apathetic mood and the desire to “just give up.”  According to Gene, the psychological symptoms were even worse than the physical ones.  For him, these included:

• Depression and anxiety

• Panic and stress

• Lack of concentration

• Mental exhaustion

• Fear of the future

For Gene, the physical symptoms of Adult Human Growth Hormone Deficiency included:

• Muscle exhaustion almost immediately upon exerting physical effort

• Persistent “baby shape” to his body, regardless of bodybuilding efforts

• Colds and other minor illnesses were absurdly debilitating

• Alcohol intolerance

Gene realized that he was not able to enjoy his life as a normal 30-year-old man should be able to.  He finally decided to speak with his doctor.

Gene’s primary care physician, knowing about his experience with Pediatric Growth Hormone Deficiency, suspected the problem had to do with Adult HGH Deficiency.  Gene was referred to an endocrinologist who performed blood work and shortly thereafter diagnosed Gene with AHGHD.

Gene and his doctor agreed that he should begin long-term HGH injection therapy right away.  Within weeks, results were evident.  Gene began to feel better in general.  He was less tired and had more energy than ever before.  Over time, his muscles were not only less tired, but also began to acquire the muscle tone and shape of adult muscles and his body began to look more normal.  Gene was able to concentrate more at work and felt less scared and anxious all the time.  He was actually energetic enough to go out in the evenings, instead of just falling into bed.  The improvement in Gene’s life over a few months of HGH replacement therapy was remarkable.  

Anti-aging

Natural Human Growth Hormone secretion is responsible for calcium retention, and strengthens and increases the bone mineralization process among other things.  As aging occurs, the production and secretion of this important hormone can be diminished considerably, which leads to symptoms of aging throughout the body.  HGH replacement therapies such as injections, sprays, pills or tablets can restore these functions and rejuvenate the human body by:

• Retaining calcium

• Strengthening bone density

• Increasing muscle mass

• Stimulating and strengthening the immune system

• Increasing protein synthesis

• Promoting the breakdown of fat stored in fat cells

• Stimulating the growth of all internal organs except the brain

• Reducing the liver’s uptake of glucose

• Promoting glucogenesis in the liver

• Contributing to the maintenance and function of pancreatic islets  

HGH for Anti-aging Case Study – “George”

George was 67 and retired.  He found himself in a stage of life that he felt was uncomfortable to the point of being unbearable.  His anxiety and stress were getting the better of him.  He felt tension more often than not and was unable to get a good night’s sleep.  He was depressed by the changes in his body.  He felt he was too young to have lost so much muscle tone, and was unwilling to resign himself to his body’s shape and condition.  George spoke with his family doctor and began taking an antidepressant.  The drug helped his mood mildly, but the state of George’s body still troubled him greatly.  George’s quality of life had taken a nosedive, and he wasn’t sure what to do.

A friend of George’s recommended an anti-aging specialist who had done wonders for her.  George decided to visit the anti-aging clinic and find out more.  “Dr. Chatzky” examined George, inquired about his own and his family’s medical history.  He took blood and ran some routine lab exams.

“Dr. Chatzky” told George about HGH replacement therapy for anti-aging.  He explained that though somewhat controversial, the treatment had improved quality of life for over 170 of his own patients.  George asked about possible risks and side effects, and ultimately decided that the benefits would outweigh them.  He began HGH injection therapy the next week.  After the 5^th day, George began to feel subtle changes in his body, though it was difficult to explain exactly what those changes were.  The very next week, he noticed that his appetite was suddenly much better – practically voracious, and that he was sleeping through the night.  Each new week of HGH replacement therapy brought new improvements – to George’s mood, to his body composition, and to his overall well-being.  In the fourth month, his wife decided she would also like to try Human Growth Hormone.

In order to save some money, George and “Martha” started looking for an online source of HGH injections they could administer themselves at home.  They found a reputable manufacturer of the injection and have been able to continue their ongoing treatment without breaking the bank.  Now, they enjoy a life full of bike rides, picnics, theater, dancing and more.  “It’s like a whole new youth!” says Martha.

For Weight-loss

Using Human Growth Hormone for healthy weight loss can be very effective if used concurrently with a nutritious and low-fat diet and a daily regimen of cardiovascular exercise.  HGH significantly enhances the body’s ability to lose weight and achieve proper muscle to fat ratios for many of the same reasons it works to alleviate AHGHD.  Because HGH replacement therapies increase muscle mass and promote the breakdown of fat stored in fat cells, weight loss becomes much easier to achieve.  Add the benefits of an improved immune system and increased energy and you’ll be on your way to a healthier body.  

HGH for Weight-loss Case Study – “Maria”

Maria led a busy life.  As a Kindergarten teacher, wife and mother, she spent most of her young life running around chasing children.  The weight problem started when she retired at age 55, shortly after her own children had gone off to college.  Maria started overeating as a coping mechanism for her “loss” of her children and career.  At the same time, the new season of life (middle age, menopause) had seemed to all but stop her slowing metabolism.  All these changes led to a weight increase that put Maria at risk of heart disease and stroke.

Maria recognized that there was a problem, and started trying different weight-loss methods in order to keep herself healthy.  She tried several different diets.  She joined her local gym and started going religiously.  Unfortunately, for all her efforts, Maria was unable to achieve any significant results.  That’s when a friend mentioned the possibility of using Human Growth Hormones as a weight-loss stimulant.  “Julia” told Maria about how she had been using HGH for years, and she described to her the overall improvements in her body.  She also told her about the easy-to-administer injections and about how she was able to order them from the Internet.

Maria started her journey by doing some research.  She found every piece of information – positive and negative ever written about the use of Human Growth Hormones for weight loss.  She realized quickly that HGH would be very effective for her purpose, but not without continuing to eat healthy, low fat meals, controlling her portions, and working out regularly.  She was also very hesitant to administer injections or even get injections at a clinic (not that she could afford it).

Fortunately, she found an HGH manufacturer that supplies the hormone in the form of tablets to be taken orally.  The manufacturer touted them as “anti-aging capsules,” which was just fine by Maria.  She verified that the tablets contained the same Human Growth Hormone as the injections her friend was taking and ordered them right away.

She started taking the HGH pills about a week later.  She took one pill per day for 5 days out of the week, then she took 2 days off.  She started noticing changes in her energy level and skin tone after about 2 weeks of therapy.  She felt healthier in general in the first month of taking HGH than she had in years.  She was also finally able to start losing some weight. 

It took Maria three months of taking HGH Tablets to lose the 25 pounds she had gained since her retirement.  She has now kept the weight off for over 3 years, though she admits that she still takes HGH.  She sees the tablets as a supplement that makes her feel and look healthy, young and beautiful.